Effects of lactoferrin on body, liver, and spleen weights, and weight gain in HFCS-induced murine HMMS.

Following 8 weeks of lactoferrin administration (0, 50, 100, and 200 mg/kg), body, liver, and spleen weights, and weight gain were significantly higher in the control group than in the naïve group (P<0.05). Body, liver, and spleen weights, and weight gain were significantly lower in the lactoferrin-treated groups than in the control group (P<0.05). Data are presented as mean ± SD (n = 10), and were analyzed using one-way ANOVAs and Duncan's multiple range test. a–d: Different letters in the same row indicate a significant difference (P<0.05).