Supplemental movies for "Development of a novel alpha7-nicotinic acetylcholine receptor-selective cell-penetrating peptide for intracellular cargo transport."

Name: Supplemental movies for " Development of a novel alpha7-nicotinic acetylcholine receptor-selective cell-penetrating peptide for intracellular cargo transport. "
Creator: figshare
Published: 2025-08-15T17:10:14+08:00

DataCite Commons2025-08-15 更新2025-09-08 收录

细胞生物学

荧光成像

数据链接：

https://figshare.com/articles/dataset/Supplemental_movies_for_i_Development_of_a_novel_alpha7-nicotinic_acetylcholine_receptor-selective_cell-penetrating_peptide_for_intracellular_cargo_transport_i_i_i_/29922584/1 数据链接链接失效反馈

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资源简介：

Supplement Video 1: 3D movie animation of α-btx-AF647-labeled N2a cells transfected with α7 nAChR and NACHO DNA, showing binding of α-btx-AF647 to the plasma membrane of cells. Note that α-btx-AF647 fluorescence is not found in the interior of the cells. Detailed information can be found in Weber et al., 2025 preprint https://doi.org/10.1101/2025.08.08.669423.Supplement Video 2: 3D movie animation of ARA-FITC-labeled α7 nAChR expressing N2a cells. Strong ARA-FITC fluorescence can be inside the cells. Detailed information can be found in Weber et al., 2025 preprint https://doi.org/10.1101/2025.08.08.669423.

补充视频1： 转染α7烟碱型乙酰胆碱受体（α7 nAChR）与NACHO DNA的、经α-银环蛇毒素-AF647（α-btx-AF647）标记的N2a细胞的3D动画影像，直观展示α-btx-AF647与细胞质膜的结合过程。需注意，α-btx-AF647的荧光信号仅定位于细胞质膜，细胞内部未检测到该荧光信号。详细信息请参见Weber等人2025年的预印本：https://doi.org/10.1101/2025.08.08.669423。补充视频2： 经ARA-FITC标记的、表达α7烟碱型乙酰胆碱受体（α7 nAChR）的N2a细胞的3D动画影像，可观察到细胞内部存在强烈的ARA-FITC荧光信号。详细信息请参见Weber等人2025年的预印本：https://doi.org/10.1101/2025.08.08.669423。

提供机构：

figshare

创建时间：

2025-08-15

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