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Supplemental movies for "<i>Development of a novel alpha7-nicotinic acetylcholine receptor-selective cell-penetrating peptide for intracellular cargo transport.</i><i>"</i>

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DataCite Commons2025-08-15 更新2025-09-08 收录
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https://figshare.com/articles/dataset/Supplemental_movies_for_i_Development_of_a_novel_alpha7-nicotinic_acetylcholine_receptor-selective_cell-penetrating_peptide_for_intracellular_cargo_transport_i_i_i_/29922584/1
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<b>Supplement Video 1:</b> 3D movie animation of α-btx-AF647-labeled N2a cells transfected with α7 nAChR and NACHO DNA, showing binding of α-btx-AF647 to the plasma membrane of cells. Note that α-btx-AF647 fluorescence is not found in the interior of the cells. Detailed information can be found in Weber et al., 2025 preprint https://doi.org/10.1101/2025.08.08.669423.<b>Supplement Video 2:</b> 3D movie animation of ARA-FITC-labeled α7 nAChR expressing N2a cells. Strong ARA-FITC fluorescence can be inside the cells. Detailed information can be found in Weber et al., 2025 preprint https://doi.org/10.1101/2025.08.08.669423.<br>

<b>补充视频1:</b> 转染α7烟碱型乙酰胆碱受体(α7 nAChR)与NACHO DNA的、经α-银环蛇毒素-AF647(α-btx-AF647)标记的N2a细胞的3D动画影像,直观展示α-btx-AF647与细胞质膜的结合过程。需注意,α-btx-AF647的荧光信号仅定位于细胞质膜,细胞内部未检测到该荧光信号。详细信息请参见Weber等人2025年的预印本:https://doi.org/10.1101/2025.08.08.669423。<b>补充视频2:</b> 经ARA-FITC标记的、表达α7烟碱型乙酰胆碱受体(α7 nAChR)的N2a细胞的3D动画影像,可观察到细胞内部存在强烈的ARA-FITC荧光信号。详细信息请参见Weber等人2025年的预印本:https://doi.org/10.1101/2025.08.08.669423。<br>
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figshare
创建时间:
2025-08-15
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