The summary of miRNA-mRNA correlation-network modules.

aThe modules in primary prostate cancer (PPC) or metastatic prostate cancer (MPC) are marked with the prefix “p-” or “m-”. The positive or negative-connection modules are marked with the extension “-ps” or “-ne”. b Only the sequence-specific DNA binding transcription factors were counted. The TF genes have been annotated to one of the five GO terms: GO: 0003700 (sequence-specific DNA binding transcription factor activity), GO: 0003702 (RNA polymerase II transcription factor activity), GO: 0003709 (RNA polymerase III transcription factor activity), GO: 0016563 (transcription activator activity), and GO: 0016564 (transcription repressor activity). c The prefix “hsa-miR” are omitted in the IDs. For a miRNA, the statistical significance of the target site enrichment level in the list of the correlated modular genes was measured by the Fisher’s exact test in reference to the level of the entire gene set. The red bold font indicates p-value <0.01.