Transcriptome analysis of Huh7 cells upon Chikungunya virus infection and capsid transfection reveals regulation of distinct cellular and metabolic pathways. Transcriptome analysis of Huh7 cells upon Chikungunya virus infection and capsid transfection reveals regulation of distinct cellular and metabolic pathways

The purpose of this study is to compare the gene profiles of chikungunya virus (CHIKV) capsid transfected and CHIKV infected Huh7 cells to identify the genes differentially expressed in the presence of the capsid protein during CHIKV infection Overall design: RNA-sequencing of Chikugunya virus capsid gene transfected, Chikungunya virus infected hepatocarcinoma cells. Transcriptome profile of mock-transfected (empty pEGFPN1 vector plasmid DNA) cells was used as a control for the study