Crystal Structure of human PARP-1 ART domain bound to inhibitor UTT93
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Crystal Structure of human PARP-1 ART domain bound to inhibitor UTT93 Descriptor: (2Z)-2-[(4-{[2-(1H-benzimidazol-2-yl)ethyl]carbamoyl}phenyl)methylidene]-3-oxo-2,3-dihydro-1-benzofuran-7-carboxamide, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 1, ... Authors: Langelier, M.F, Pascal, J.M. Deposit date: 2019-01-23 Release date: 2019-08-14 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. J.Med.Chem., 62, 2019
创建时间：
2019-01-23
