Expression data from non-tumorous liver from chemically-induced hepatocellular carcinoma of wild-type or G9a deficient mice

Epigenetic gene regulation in various oncogenic pathways is currently an important focus of cancer research. Histone modification plays a pivotal role in human carcinogenesis, but the significance of histone modification in hepatocarcinogenesis remains unknown. We used microarrays to investigate the oncogenic gene regulation by histone methylase G9a in chemically-induced murine hepatocellular carcinioma model. We investigate the role of a histone methylase G9a in liver tumor development utilizing liver-specific G9a-deficient mice. We obtained the material specimen from non-tumorous liver tissue and analyze it.