The 1.6A Crystal Structure of Humanized Xenopus MDM2 with RO5027344
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The 1.6A Crystal Structure of Humanized Xenopus MDM2 with RO5027344 Descriptor: (3S)-3-[(3R)-1-acetylpiperidin-3-yl]-6-chloro-3-(3-chlorobenzyl)-1,3-dihydro-2H-indol-2-one, E3 ubiquitin-protein ligase Mdm2, SULFATE ION Authors: Graves, B.J, Lukacs, C, Kammlott, U. Deposit date: 2013-07-28 Release date: 2014-07-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Discovery of potent and selective spiroindolinone MDM2 inhibitor, RO8994, for cancer therapy. Bioorg.Med.Chem., 22, 2014
创建时间：
2013-07-28
