Structure of CHK1 10-pt. mutant complex with aminopyridine LRRK2 inhibitor
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Structure of CHK1 10-pt. mutant complex with aminopyridine LRRK2 inhibitor Descriptor: 5-[4-(morpholin-4-ylmethyl)phenyl]-3-(1-propan-2-yl-1,2,3-triazol-4-yl)pyridin-2-amine, Serine/threonine-protein kinase Chk1 Authors: Dokurno, P, Williamson, D.S, Acheson-Dossang, P, Chen, I, Murray, J.B, Shaw, T, Surgenor, A.E. Deposit date: 2017-08-10 Release date: 2017-10-25 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1). J. Med. Chem., 60, 2017
创建时间：
2017-08-10
