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Mutant Mus Musculus P38 Kinase Domain in Complex with Inhibitor PG-874743

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Protein Data Bank Japan2024-02-14 更新2026-03-21 收录
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https://pdbj.org/mine/summary/2ghl
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Mutant Mus Musculus P38 Kinase Domain in Complex with Inhibitor PG-874743 Descriptor: 3-(2-CHLOROPHENYL)-1-(2-{[(1S)-2-HYDROXY-1,2-DIMETHYLPROPYL]AMINO}PYRIMIDIN-4-YL)-1-(4-METHOXYPHENYL)UREA, Mitogen-activated protein kinase 14 Authors: Walter, R.L, Mekel, M.J, Evdokimov, A.G, Pokross, M.E, Brugel, T.A. Deposit date: 2006-03-27 Release date: 2006-04-11 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.099 Å) Cite: Development of N-2,4-pyrimidine-N-phenyl-N'-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 1. Bioorg.Med.Chem.Lett., 16, 2006
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2006-03-27
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