Fundus vessel phenotypes

Related publication (2024): https://www.nature.com/articles/s41467-024-52334-1

Sumstat column information

beta: refers to the effect of having an extra copy of A2

af: frequency of A2

A2 is not necessarily the minor allele

The sumstats are curated bgenie output. official bgenie manual: https://jmarchini.org/bgenie/#output-file-options

Label map (maps names used in the paper to the sumstat labels)

tif_dict = { 'A temporal angle': 'mean_angle_taa', 'V temporal angle': 'mean_angle_tva', 'V tortuosity': 'tau1_vein', 'A tortuosity': 'tau1_artery', 'ratio tortuosity': 'ratio_AV_DF', 'A central retinal eq': 'eq_CRAE', 'ratio central retinal eq': 'ratio_CRAE_CRVE', 'A std diameter': 'D_A_std', 'V std diameter': 'D_V_std', 'V central retinal eq': 'eq_CRVE', 'ratio vascular density': 'ratio_VD', 'A vascular density': 'VD_orig_artery', 'bifurcations': 'bifurcations', 'V vascular density': 'VD_orig_vein', 'A median diameter': 'medianDiameter_artery', 'V median diameter': 'medianDiameter_vein', 'ratio median diameter': 'ratio_AV_medianDiameter' }