five

Isocyanide-Based Multicomponent Bicyclization with Substituted Allenoate and Isatin: Synthesis of Unusual Spirooxindole Containing [5.5]-Fused Heterocycle

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NIAID Data Ecosystem2026-03-09 收录
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https://figshare.com/articles/dataset/Isocyanide-Based_Multicomponent_Bicyclization_with_Substituted_Allenoate_and_Isatin_Synthesis_of_Unusual_Spirooxindole_Containing_5_5_-Fused_Heterocycle/3860271
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资源简介:
A three-component bicyclization reaction of isocyanide, substituted allenoate, and isatin has been disclosed. This protocol is proposed to proceed through Michael addition, double cyclization, and [1,5]-hydride shift sequence, thus leading to the formation of two new rings and five new chemical bonds, including C–C, C–O, and C–N bonds.
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2016-10-03
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