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Role of activated PI3K-delta signaling in humoral immunity. Role of activated PI3K-delta signaling in humoral immunity

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA720927
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We report the high-throughput profiling of murine naive B cells, germinal center (dark zone and light zone) B cells, and plasma cells transcriptome. By obtaining over 5 million bases of sequence, we generated genome-wide expression maps of cell subsets from WT mice and aPIK3CD mice. We find that activated PIK3CD signaling lead to significant alteration in gene expression of plasma cells. Overall design: Transcriptome profiling of naïve B cells, germinal centers (dark zone and light zone) B cells, and plasma cells to determine the effect of activated PIK3CD signaling
创建时间:
2021-04-09
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