Crystal structure of Tdp1 catalytic domain in complex with compound XZ519
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Crystal structure of Tdp1 catalytic domain in complex with compound XZ519 Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-8-nitroquinoline-3-carboxylic acid, Tyrosyl-DNA phosphodiesterase 1 Authors: Lountos, G.T, Zhao, X.Z, Kiselev, E, Tropea, J.E, Needle, D, Burke Jr, T.R, Pommier, Y, Waugh, D.S. Deposit date: 2018-09-20 Release date: 2019-07-03 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.853 Å) Cite: Identification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment cocktail screening. Nucleic Acids Res., 47, 2019
创建时间：
2018-09-20
