Gene expression profiling of chondrodysplasia mutants and isogenic controls during hypertrophic induction from iPSCs
收藏NIAID Data Ecosystem2026-03-12 收录
下载链接：
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE148728
下载链接
链接失效反馈官方服务：
资源简介：
In order to better understand chondrodysplasia disease mechanisms, we induced hypertrophic chondrocytes from chondrodysplasia-specific iPSCs and analyzed their gene expression profile. This dataset includes the expression data obtained from iPSC-derived cartilage pellets on day 56 of hypertrophic induction. Three COL10A1 mutants and two MATN3 mutants were compared to their isogenic controls to determine the effects of each mutation on the unfolded protein response. A total of 27 samples (5 mutants and 4 isogenic controls, each with 3 biological replicates) were analyzed.
创建时间：
2021-02-27
