A clinical trial on determination of the blood concertration of 5-fluorouracil in Chinese patients with colorectal cancer and validaton of the ideal therapeutic window by a fast blood test kit

Interventions: group of dosing adjusted by TDM:adjusted dose of 5-Fu by TDM;group of dosing adjusted by BSA:adjusted dose of 5-Fu by BSA Primary outcome(s): OR;blood concentration of 5-Fu Study Design: Randomized parallel controlled trial