Global reconstruction of 5-HT2AR bound to LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)

Protein Data Bank Japan2025-06-04 更新2026-06-30 收录

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Global reconstruction of 5-HT2AR bound to LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM) Descriptor: (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, 5-hydroxytryptamine receptor 2A, G subunit q (Gi2-mini-Gq chimeric), ... Authors: Gumpper, R.H, Fay, J.F, Roth, B.L. Deposit date: 2024-02-24 Release date: 2025-04-02 Last modified: 2025-06-04 Method: ELECTRON MICROSCOPY (3.06 Å) Cite: The structural diversity of psychedelic drug actions revealed. Nat Commun, 16, 2025

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2024-02-24