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Crystal structure of Aurora-A kinase in complex with an allosterically binding fragment

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Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Crystal structure of Aurora-A kinase in complex with an allosterically binding fragment Descriptor: (1~{R})-1-(4-ethoxyphenyl)ethanamine, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ... Authors: McIntyre, P.J, Collins, P.M, von Delft, F, Bayliss, R. Deposit date: 2017-08-16 Release date: 2017-11-01 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches. ACS Chem. Biol., 12, 2017
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2017-08-16
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