Single-cell RNA sequencing of meningiomas

We report single-cell RNA sequencing of 57,114 cells from 8 meningioma samples and 2 dura samples, which are used to analyze the inter- and intra-meningioma heterogeneity across DNA methylation groups. A total of 10 tissue samples from 6 meningioma patients were analyzed. Two patients had 2 pieces each of their meningiomas analyzed, one from the bulk of the tumor and another from the brain-tumor interface (BTI). 2 patients also had dura tissue from their meninges analyzed as well as a normal tissue control.