A longitudinal study of MRSP-carriage

Despite a worldwide increase in presence of methicillin-resistant S. pseudintermedius (MRSP) in dogs and its potential to cause serious canine health problem, the understanding of transmission and long-term carriage of MRSP is limited. The results of this longitudinal study of MRSP-carriage were intended to add to knowledge needed for development of effective preventative measures regarding further transmission of MRSP. The use of whole-genome sequencing in investigations of the epidemiology of MRSP was to be evaluated through investigation of isolates of known origin. MRSP-carriage was investigated over several months in 11 dogs living in four separate multiple dog households where an MRSP infection had been diagnosed. Whole-genome sequencing was used for genotypic characterization of cultured MRSP isolates.