Supplementary Tables from Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability–High Colorectal Cancers
收藏资源简介:
Supplementary Tables S1-S12: Supplementary Table S1: Primer sequences used in this study. Supplementary Table S2: Clinical information of tumours analysed in the present study. Supplementary Table S3: Patients' characteristics. Supplementary Table S4: Likely causal mutations in mismatch repair genes detected in this study. Supplementary Table S5: List of Tier 2 mutations. Supplementary Table S6: Significantly mutated genes identified with MutSigCV. Supplementary Table S7: Genes differentially altered between Lynch syndrome-associated/Lynch-like tumours and MLH1 promoter-methylated tumours. Supplementary Table S8: Recurrent copy number alterations detected with allele-specific copy number analysis. Supplementary Table S9: Pathways detected from top 209 Tier 2 genes with The Database for Annotation, Visualization and Integrated Discovery. Supplementary Table S10: Pathways detected from significantly mutated genes with The Database for Annotation, Visualization and Integrated Discovery. Supplementary Table S11: Detected oncogenic alterations and associated mutations with uncertain significance. Supplementary Table S12: Complementary DNA sequences of fusion points confirmed by reverse-transcription polymerase chain reaction followed by Sanger sequencing.



