RNA-seq of Lin-CD34+ cord-blood cells expressing shRNA against PLAG1 or control [KD]
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https://www.ncbi.nlm.nih.gov/sra/SRP332281
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资源简介：
To characterize transcriptional changes associated with loss of the transcription factor PLAG1-S that could contribute to PLAG1 essentiality in long-term human HSC we performed RNA-seq of 2 pools of Lin-CD34+ cord-blood derived hematopoietic stem and progenitor cells 72 hours following lentiviral introduction of shRNA against PLAG1 or non-targeting control. Overall design: Lin-CD34+ samples from 2 biologically distinct pools of CB were transduced to express shPLAG1 or shControl, and 72 hours following viral introduction transduction marker positive cells were FACS-isolated for bulk RNA-seq.
创建时间：
2022-12-02
