Crystal structure of renin in complex with NVP-AYZ832 (compound 6a)
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Crystal structure of renin in complex with NVP-AYZ832 (compound 6a) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-{[(3S,4S)-4-benzylpyrrolidin-3-yl]methyl}-4-chloro-N-phenylaniline, Renin, ... Authors: Ostermann, N, Zink, F, Kroemer, M. Deposit date: 2012-08-09 Release date: 2013-03-06 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.58 Å) Cite: The Discovery of Novel Potent trans-3,4-Disubstituted Pyrrolidine Inhibitors of the Human Aspartic Protease Renin from in Silico Three-Dimensional (3D) Pharmacophore Searches. J.Med.Chem., 56, 2013
创建时间:
2012-08-09



