Crystal structure of MAT2a bound to allosteric inhibitor (compound 31)
收藏Protein Data Bank Japan2024-05-01 更新2026-03-21 收录
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Crystal structure of MAT2a bound to allosteric inhibitor (compound 31) Descriptor: 7-chloranyl-4-(dimethylamino)-1-pyridin-3-yl-quinazolin-2-one, CHLORIDE ION, DIMETHYL SULFOXIDE, ... Authors: Schimpl, M, De Fusco, C, Borjesson, U, Cheung, T, Collie, I, Evans, L, Narasimhan, P, Stubbs, C, Vazquez-Chantada, M, Wagner, D.J, Grondine, M, Tentarelli, S, Underwood, E, Argyrou, A, Bagal, S, Chiarparin, E, Robb, G, Scott, J.S. Deposit date: 2021-01-11 Release date: 2021-04-21 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.08 Å) Cite: Fragment-Based Design of a Potent MAT2a Inhibitor and in Vivo Evaluation in an MTAP Null Xenograft Model. J.Med.Chem., 64, 2021
创建时间：
2021-01-11
