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Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with a mechanism-based inhibitor

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Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with a mechanism-based inhibitor Descriptor: 1,2-ETHANEDIOL, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, DI(HYDROXYETHYL)ETHER, ... Authors: Maize, K.M, Eiden, C, Aldrich, C.C, Finzel, B.C. Deposit date: 2016-09-20 Release date: 2017-05-31 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Rational Optimization of Mechanism-Based Inhibitors through Determination of the Microscopic Rate Constants of Inactivation. J. Am. Chem. Soc., 139, 2017
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2016-09-20
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