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Synthesis of cyclopropyl-substituted furans by Brønsted acid promoted cascade reactions

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DataCite Commons2020-08-19 更新2025-04-17 收录
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资源简介:

Chloroacetic acid promotes an efficient and diastereoselective intramolecular cascade reaction of electron-deficient ynenones to deliver products featuring a 2,3,5-trisubstituted furan bearing a fused cyclopropyl substituent at the 5-position. Synthetically relevant polycyclic building blocks featuring rings of various sizes and heteroatoms have been synthesized in high yield using this mild acid-catalyzed reaction.

提供机构:
University of Glasgow
创建时间:
2015-05-14
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