Molecular and functional characterization of haematopoietic stem cells (HSCs) in a mouse model of myeloproliferative neoplasm [RNA-seq]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE169243
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资源简介：
We report the characterization of murine HSCs with knock-in of human JAK2V617F, Ezh2 loss, and both hits, through RNA-seq on a limited number of HSCs. We identified Ezh2 loss as being a strong driver of gene expression differences, while gene set enrichment analysis showed unique signatures characterizing mutant HSCs. mRNA profiles of HSCs in four groups: control, JAK2V617F, Ezh2 loss, JAK2V617F + Ezh2 loss.
创建时间：
2021-07-09
