YBX1-dependent LNA-tRF-mediated modulation of gene expression. Homo sapiens
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA268376
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资源简介:
In order to identify YBX1-dependent targets that are modulated upon changing the levels of endogenous tRFs, we used transient transfection of antisense locked-nucleic acids (LNAs) against tRFAsp, tRFGly, tRFGlu, and tRFTyr followed by microarray profiling. Overall design: Synthetic antisense locked-nucleic acids (LNAs) targeting the YBX1 binding site on tRFAsp, tRFGly, tRFGlu, and tRFTyr were transfected into control and YBX1-knockdown cells to identify YBX1-dependent targets that are modulated due to tRF loss-of-function.
创建时间:
2014-11-21



