Crystal structure of BACE1 in complex with 2-aminooxazoline 3-azaxanthene inhibitor 28
收藏Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Crystal structure of BACE1 in complex with 2-aminooxazoline 3-azaxanthene inhibitor 28 Descriptor: (5S)-7-(2-fluoropyridin-3-yl)-3-(2-fluoropyridin-4-yl)spiro[chromeno[2,3-c]pyridine-5,4'-[1,3]oxazol]-2'-amine, Beta-secretase 1, GLYCEROL, ... Authors: Whittington, D.A, Long, A.M. Deposit date: 2015-01-12 Release date: 2015-02-04 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious beta-secretase inhibitors for the potential treatment of Alzheimer's disease. Bioorg.Med.Chem.Lett., 25, 2015
创建时间：
2015-01-12
