Atomistic ensemble of active SHP2
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资源简介：
SHP2 phosphatase plays an important role in regulating several intracellular signaling pathways. Pathogenic mutations of SHP2 cause developmental disorders and are linked to hematological malignancies and cancer. This dataset contains the atomistic ensemble of the constitutively active E76K mutant of SHP2 generated by molecular dynamics simulations in solution and validated by accurate explicit-solvent SAXS curve predictions.
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Zenodo创建时间：
2023-10-31
