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Actinomycin D-induced mitochondrial stress targets PML during NPM1c-AML therapy

ChEBI2021-05-10 更新2026-07-12 收录

急性髓系白血病

线粒体应激机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-10397 数据链接链接失效反馈

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资源简介：

Actinomycin D-induced mitochondrial stress targets PML during NPM1c-AML therapy

应用场景：

创建时间：

2021-05-10

急性髓系白血病

RNA测序

We investigated the role of the transcriptional regulators Id2 and E2-2 (encoded by Tcf4) in the context of MLL-rearranged acute myeloid leukemia (AML). Using an AML mouse model driven by a Tet-off in

干细胞与再生医学数据中心2022-02-20 更新80

Supplementary Table 2 from Disruption of the MYC Superenhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia

急性髓系白血病

转录因子调控

Transcription Factor Enrichment Analysis of MOLM13 Bulk RNA-Seq (24 Hours After Drug Treatment)

Figshare2023-07-05 更新40

Clinical and molecular characteristics of the 70 patients with AML at diagnosis included in the study.

急性髓系白血病

肿瘤基因组学

Clinical and molecular characteristics of the 70 patients with AML at diagnosis included in the study.

Figshare2015-12-02 更新10

RNA sequencing analysis of murine MLL-AF9 acute myeloid leukemia cells expressing different levels of Id2 and Kit

急性髓系白血病

RNA测序

We investigated the role of the transcriptional regulator Id2 in the context of MLL-rearranged acute myeloid leukemia (AML). Using an Id2/GFP-reporter mouse model of MLL-AF9-driven AML, we showed that

干细胞与再生医学数据中心2022-02-20 更新50

Additional file 2: of BCL2 overexpression: clinical implication and biological insights in acute myeloid leukemia

急性髓系白血病

基因表达

Different expressed genes of microRNA for BCL2high and BCL2low. (XLSX 50 kb)

DataCite Commons2024-03-01 更新30