Extracellular vesicles-enclosed miRNA deregulation upon BRAFV600E induction in mouse thyrocytes
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA878686
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资源简介：
Papillary thyroid cancer (PTC) is the most common endocrine malignancy for which diagnosis and recurrences still challenge clinicians. New perspectives to overcome these issues could come from the study of extracellular vesicle (EV) populations and content. Here, we aimed to elucidate the heterogeneity of EVs circulating in the tumor and the changes in their microRNA content during cancer progression. Using a mouse model expressing BRAFV600E, we isolated and characterized EVs from thyroid tissue by ultracentrifugations and elucidated their microRNA content by small RNA sequencing.
创建时间：
2022-09-09
