Additional file 2 of Genomics of asthma, allergy and chronic rhinosinusitis: novel concepts and relevance in airway mucosa

Additional file 2: Table S2. Integrated data from GWAS catalog on asthma, allergy/AR and CRS -associating SNPs, the corresponding proteins of which have evidence of human airway epithelial expression from manual literature search. The list of 170 asthma/AR –relevant coding gene names were identified based on GWAS search shown in Fig. 1. We detected that 145/170 genes have reported epithelial gene and/or protein expression based on systematic Human Protein Atlas (HPA) search. We detected that 86/170 genes have at least slight evidence of airway epithelial expression based on literature search, the citations are shown in the list. Abbreviations: Protein_Atlas_Lung_Expression(TPM02) = 0 = TPM less than 1; 1 = 1 < TPM < 100; 2 = TPM 100 or over, Protein_Atlas_Lung_Expression(TPM) = total TPM value, HPA BrProt exp epi = Bronchial epithelial protein expression of immunohistochemical staining figures of The Human Protein Atlas, HPA Br Prot exp = Bronchial protein expression of immunohistochemical staining figures of The Human Protein Atlas, HPA Nasoph Prot exp epi = Nasopharyngeal epithelial protein expression of immunohistochemical staining figures of The Human Protein Atlas, HPA Nasoph Prot exp = Nasopharyngeal protein expression of immunohistochemical staining figures of The Human Protein Atlas, HPA Nasoph GTEx (RPKM) = The Genotype-Tissue Expression (GTEx) of Nasopharyngeal mucosa of The Human Protein Atlas, RPKM = Reads Per Kilobase of transcript, per Million mapped reads, HPA Bronch GTEx (RPKM) = The Genotype-Tissue Expression (GTEx) of Bronchial mucosa of The Human Protein Atlas, GXA = Gene Expression Database, Literat_Resp_epith = Literature search result of Airway expression: 0 = no/not known; 1 = some evidence; 2 = evidence exists, Literat Ref (PMID) = PubMed ID for the Literature search result.