Nrf2 and HIF1α merge to arsenic-induced metabolic reprogramming and formation of the cancer stem-like cells.
收藏NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE145834
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资源简介：
Arsenic (iAs) induces generation of the cancer stem-like cells (CSCs) through Nrf2-dependent HIF1α activation, and the subsequent metabolic reprogramming from mitochondrial oxdaive phosphorylation to glycolysis in epithelial cells. Genome-wide ChIP-seq analysis of the global binding of Nrf2 (sc-13032) and/or HIF1α (ab2185) on the genome in the cells treated with iAs (1 μM for 6 hrs).
创建时间：
2020-05-26
