The in situ detection of caspase-3 activity has applications in the imaging and monitoring of multiple pathologies, notably cancer. A series of cell penetrating FRET-based fluorogenic substrates were
Cells (2×10 5 ) were cultured in 6-well plates, and then were incubated with sunitinib for 24 hr. Necrosis was analyzed using the Annexin V-FITC/PI Apoptosis Detection Kit (40302ES50, Yeasen
The number of cells per wound was derived from counting of cells in a single cell suspension derived from digestion of an entire wound. Values represent means±SD, n = 6 or 7. In Balb/C recipient mice,
