Reference of endogenous and pluripotent stem-cell derived cardiomyocyte maturation
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE164591
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The purpose of this study was to understand differences between maturation processes in endogenous and pluripotent stem cell-derived cardiomyocytes. To this end, we first expanded our previous reference of endogenous cardiomyocyte maturation, isolated by LP-FACS (see Kannan et al., bioRxiv 2020, and GSE147807). We subsequently generated PSCs from the same background strain and differentiated to CMs. CMs were isolated by conventional FACs. We isolated CMs from mice at the following timepoints (using LP-FACS for all timepoints from p8 onwards): e14, e18, p0, p1, p4, p8, p11, p14, p15, p18, p22, p28, p35, p56, and p84. We isolated PSC-CMs at D8, D10, D12, D15, D18, D25, D30, and D45.
创建时间：
2021-01-14
