Carcinogenic Potency Database (CPDB) - Archived Data

Carcinogenic Potency Database (CPDB) is a single standardized resource of the results of 45 years of chronic, long-term carcinogenesis bioassays. The experiments vary widely in design, histopathological examination and nomenclature, and in the published authors’ choices of what information to publish in their papers. Data are included from 6153 experiments reported in the general literature and in the in Technical Reports of the National Cancer Institute/National Toxicology Program (NCI/NTP). Information is given in the CPDB on strain, sex, route of compound administration, target organ, histopathology, author’s opinion about carcinogenicity, and reference to the published paper, as well as quantitative data on statistical significance, tumor incidence, dose-response curve shape, length of experiment, duration of dosing, and dose-rate. The files on this Web site for the Excel format include (A) documentation of methods, field descriptions, and linking instructions; (B) Excel files; and (C) ancillary files of appendices. NOTE: This dataset is no-longer updated with new content.

致癌性效力数据库（Carcinogenic Potency Database，CPDB）是一套标准化的单一资源，整合了45年间的慢性长期致癌生物检测结果。相关实验在实验设计、组织病理学检查规范、术语命名体系，以及作者在发表论文时选择披露的信息范畴上均存在显著差异。该数据库收录了来自公开学术文献以及美国国家癌症研究所/国家毒理学计划（National Cancer Institute/National Toxicology Program，NCI/NTP）技术报告中的6153项实验数据。CPDB所收录的信息涵盖：实验动物品系、受试动物性别、化合物给药途径、靶器官、组织病理学结果、作者对受试物致癌性的评估意见、相关学术论文的参考文献，同时还包含统计学显著性水平、肿瘤发生率、剂量-反应曲线形态、实验总时长、给药持续时间以及给药速率等定量数据。本网站提供的Excel格式文件包含三类内容：(A) 实验方法文档、字段说明及数据关联指南；(B) Excel数据文件；(C) 附录类辅助文件。注意：本数据集已停止更新，不再新增内容。