CDK2 in complex with a disubstituted 2, 4-bis anilino pyrimidine CDK4 inhibitor
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https://pdbj.org/mine/summary/1h08
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CDK2 in complex with a disubstituted 2, 4-bis anilino pyrimidine CDK4 inhibitor Descriptor: (2R)-1-{4-[(4-ANILINO-5-BROMOPYRIMIDIN-2-YL)AMINO]PHENOXY}-3-(DIMETHYLAMINO)PROPAN-2-OL, (2S)-1-{4-[(4-ANILINO-5-BROMOPYRIMIDIN-2-YL)AMINO]PHENOXY}-3-(DIMETHYLAMINO)PROPAN-2-OL, CELL DIVISION PROTEIN KINASE 2, ... Authors: Breault, G.A, Ellston, R.P.A, Green, S, James, S.R, Jewsbury, P.J, Midgley, C.J, Minshull, C.A, Pauptit, R.A, Tucker, J.A, Pease, J.E. Deposit date: 2002-06-11 Release date: 2003-07-11 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Cyclin-Dependent Kinase 4 Inhibitors as a Treatment for Cancer. Part 1: Identification and Optimisation of Substituted 4,6-Bis Anilino Pyrimidines Bioorg.Med.Chem.Lett., 13, 2003
创建时间：
2002-06-11
