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Crystal Structure of Ack1 with compound T74

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Protein Data Bank Japan2023-12-27 更新2026-03-21 收录
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Crystal Structure of Ack1 with compound T74 Descriptor: Activated CDC42 kinase 1, CHLORIDE ION, N~3~-(2,6-dimethylphenyl)-1-(3-methoxy-3-methylbutyl)-N~6~-(4-piperazin-1-ylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine Authors: Liu, J, Wang, Z, Walker, N.P.C. Deposit date: 2008-10-01 Release date: 2008-12-02 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Identification and optimization of N3,N6-diaryl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamines as a novel class of ACK1 inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
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2008-10-01
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