Supplemental material for: Growth curves for children with X-linked hypophosphatemia\"

Context: We characterized linear growth in infants and children with X-linked hypophosphatemia (XLH). Objective: Provide linear growth curves for children with XLH from birth to early adolescence. Design: Data from four prior studies of XLH were pooled to construct growth curves. UX023-CL002 was an observational, retrospective chart review. Pre-treatment data were collected from three interventional trials: two phase 2 trials (UX023‑CL201, UX023‑CL205) and a phase 3 trial (UX023-CL301). Setting: Medical centers with expertise in treating XLH. Patients: Children with XLH, 1-14 years of age. Intervention: None. Main Outcome Measure: Height-for-age linear growth curves including values for the 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentiles for children with XLH compared to population norms. Results: 228 patients (132 girls, 96 boys) with 2,381 height measurements were included. Nearly all subjects (>99%) reported prior management with supplementation th...