Cyclopentadiene–Phosphine/Palladium-Catalyzed Cleavage of C–N Bonds in Secondary Amines: Synthesis of Pyrrole and Indole Derivatives from Secondary Amines and Alkenyl or Aryl Dibromides
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https://figshare.com/articles/dataset/Cyclopentadiene_Phosphine_Palladium_Catalyzed_Cleavage_of_C_N_Bonds_in_Secondary_Amines_Synthesis_of_Pyrrole_and_Indole_Derivatives_from_Secondary_Amines_and_Alkenyl_or_Aryl_Dibromides/2459260
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资源简介：
An efficient Pd-catalyzed cleavage of C(sp3)–N
bonds in secondary amines and a consequent C(sp2)–N
and C(sp3)–N coupling process was developed. Various
secondary amines could be used to react with alkenyl or aryl dibromides,
affording pyrroles and indoles in high yields. Cyclopentadiene–phosphine
ligands, a new type of P–olefin ligand, were found to be able
to promote the efficiency of this Pd-catalyzed process remarkably.
A reactive Pd complex coordinated with a cyclopentadiene–phosphine
ligand was successfully isolated and structurally characterized.
创建时间：
2016-02-20
