Adipocyte-derived FABP4 promotes MASLD-induced hepatocellular carcinoma by driving ITGB1-mediated β-catenin activation
收藏NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE286130
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资源简介：
The mechanism underlying regulatory role of FABP4 in MASLD-HCC development was examined using bulk RNA sequencing. Chemically induced MASLD-HCC model was generated using male wildtype and Fabp4 knockout C57BL/6N mice. They were treated with N-nitrosodiethylamine at 25mg/kg intraperitoneally at the age of 14 days. Starting at 6 weeks of age, they were fed with high fat diet for 29 weeks. Tumor nodules in the livers were extracted for bulk RNA sequencing.
创建时间：
2025-10-02
