Muscle stem cells (MuSCs) are requisite for skeletal muscle regeneration and homeostasis. Mechanically loaded MuSCs within their native niche undergo tensile and shear deformations, but how MuSCs sens
Metastatic cells migrate from the site of the primary tumor, through the stroma, into the blood and lymphatic vessels, finally colonizing various other tissues to form secondary tumors. Numerous studi
Mechanical cues play a vital role in numerous biological processes, including embryonic development, aging, cellular homeostasis, and disease progression. Cells sense and convert these mechanical sign
The arterial endothelium’s response to its flow environment is critical to vascular homeostasis. The endothelial glycocalyx has been shown to play a major role in mechanotransduction, but the extent t
The behavior of cells is governed by signals originating from their local environment, including mechanical forces that cells experience. Forces are transduced by mechanosensitive proteins, which can
