CancerTope: A Platform for Designing Genome-Based Personalized Immunotherapy or Vaccine against Cancer

Welcome to the official repository for Cancertope, a computational platform and database for identifying cancer-specific neoepitopes and designing personalized cancer vaccines and immunotherapies. This resource integrates mutational data, immune epitope prediction, and vaccine candidate prioritization into a unified framework. Citation If you use Cancertope, please cite: Gupta et al. (2016) A Platform for Designing Genome-Based Personalized Immunotherapy or Vaccine against Cancer PLOS ONE DOI: https://doi.org/10.1371/journal.pone.0166372 About the Platform Cancertope is designed to address a key bottleneck in cancer immunotherapy: Identifying tumor-specific antigens (neoantigens) that can trigger a targeted immune response. Traditional experimental methods are: Costly Time-consuming Not scalable Cancertope solves this using computational pipelines + large-scale mutation data. It analyzes: Somatic mutations Cancer-specific protein regions Immune epitope potential and converts them into actionable vaccine candidates .