Aging Promotes Metabolic Dysfunction-Associated Steatotic Liver Disease by Inducing Ferroptotic Stress
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE262939
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Aging increases the risk for failure of many metabolically-stressed organs and exacerbates liver degeneration related to obesity and diabetes. We used snRNA-seq to identify the effect of metabolic disease (MASLD) on biological aging of hepatocyte. 12 weeks old C57BL/6J male mice were fed with either chow or CDA-HFD for 22 weeks, and nuclei were isolated from liver tissues for snRNA-seq analysis
创建时间：
2025-04-10
