Our study presents a spatial-stochastic model for the gene regulatory network (GRN) and the signaling pathway governing cell-fate differentiation during early mouse embryogenesis, specifically at the
Single-cell approaches are revealing a high degree of heterogeneity, or noise, in gene expression in isogenic bacteria. How gene circuits modulate this noise in gene expression to generate robust outp
BPTTGA is the parameter estimation method of Vohradský's models, that is designed on the basis of the back-propagation through time [33]. As a function optimizer, BPTTGA used an evolutionary algorithm