Sex is a Significant Effect Modifier.

Beta = regression coefficient; CI = confidence interval; OASMa = Overt-Aggression-Scale-Modified–Aggression-Subscale; Prava = pravastatin; SE = standard error; Simva = simvastatin. Regressions (robust SEs) adjust for baseline OASMa, as a primary source of change variance; the sex-interaction, and (as required) the individual components of the interaction term. Excludes outliers (OASMa absolute change >40 points). Without exclusion of outliers: Results lose significance for the full group. Results remain identical for the No Baseline Aggression group (all aggression outliers had nonzero baseline aggression). Sex-by-Statin Interaction Term Significance.