[Dataset] Multidisciplinary evaluation of biofabricated starch nanoscaffolds incorporating phyto-synthesized CuO nanoparticles from Dictyota extract

This dataset provides a multidisciplinary assessment of starch-based nanoscaffolds integrated with copper oxide nanoparticles (CuO NPs) synthesized using Dictyota sp., a brown macroalga, as a sustainable phytoreduction agent. UV-visible spectroscopy (UV-Vis) confirms CuO NP formation via characteristic plasmonic absorption bands, while Fourier-transform infrared spectroscopy (FT-IR) identifies functional groups in the algal extract (e.g., polyphenols, polysaccharides) involved in nanoparticle synthesis and stabilization, alongside interactions (e.g., hydrogen bonding) between starch polymers and CuO NPs. X-ray diffraction (XRD) validates the crystalline structure and phase purity of the nanoparticles, and scanning electron microscopy (SEM) reveals the nanoscaffold’s porous architecture, surface morphology, and homogeneous nanoparticle dispersion. Thermal gravimetric analysis (TGA) quantifies thermal stability, demonstrating enhanced degradation resistance of the nanocomposite due to CuO NP reinforcement. Dynamic light scattering (DLS) profiles nanoparticle hydrodynamic size, polydispersity, and colloidal stability, essential for biocompatibility evaluation. The dataset underscores the efficacy of Dictyota extract in enabling eco-friendly CuO NP synthesis while improving scaffold properties, such as mechanical robustness, controlled biodegradation, and thermal resilience. These biofabricated nanocomposites hold potential for biomedical applications, including tissue engineering, antimicrobial coatings, or drug delivery systems, where sustainable materials are prioritized. By combining green synthesis with advanced analytical workflows, this resource bridges phytochemistry, material science, and nanotechnology, offering insights into scalable, low-toxicity biomaterial design. Researchers can leverage this multidisciplinary framework to optimize algal-mediated synthesis protocols, correlate structural features with functional performance, and engineer starch-based nanohybrids for targeted ecological and biomedical innovations. The work highlights the role of marine algae in advancing eco-conscious nanotechnology and circular material economies.