Effect of tempol on cisplatin-induced changes in mitochondrial complexes I–IVactivities, oxidative phosphorylation capacity and adenosine triphosphate (ATP) content in renal tissues of mice.
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Mice were studied 72 h after a single i.p. injection of cisplatin (25 mg/kg). Tempol (100 mg/kg/day) was given orally for 4 days starting one day before cisplatin injection. Each value represents the mean of 6–8 mice ± S.E.M. *p normal, #p. cisplatin.Effect of tempol on cisplatin-induced changes in mitochondrial complexes I–IVactivities, oxidative phosphorylation capacity and adenosine triphosphate (ATP) content in renal tissues of mice.
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2015-12-02
