Impact of Faecalibacterium spp. on gut microbiota in female mice under different dietary conditions

This study examines the effects of different Faecalibacterium species on gut microbiota in female mice under two dietary conditions: normal and low-fiber diet. The bacterial strains Faecalibacterium duncaniae A2-165, Faecalibacterium longum Fl-1 and Fl-2, and Faecalibacterium butyricigenerans Fb-1 were orally administered, along with a control group receiving medium. Cecal content samples were collected, and 16S rRNA sequencing targeting the V3-V4 region was performed to analyze gut microbiota composition.