Human PRPF40B knock-out in K562 CML cell line
收藏NIAID Data Ecosystem2026-05-26 收录
官方服务：
资源简介：
We characterized the transcriptomic regulation of PRPF40B, which is a splicing factor mutated in a small fraction of MyeloDysplastic Syndromes (MDS) patients. We generated a full PRPF40B knockout in K562 cell line by CRISPR/Cas9 technology, and rescued its levels by transient overexpression of wild-type, P383L or P540S MDS alleles.
创建时间：
2019-05-09
